In acute renal failure, it is possible to increase the glomerular filtration rate from 40 ml/min to 69 ml/min; in case of chronic renal failure, it is unlikely. Acute renal failure, most often seen in fever, diarrhea, gastrointestinal bleeding, heart failure, drug damage, urinary tract obstruction, etc., generally correct the causative factors, glomerular filtration rate can be returned to normal. Chronic renal failure, most often due to glomerulonephritis, diabetic nephropathy, hypertensive nephropathy, etc., in general, although timely treatment, the condition is difficult to recover, and the glomerular filtration rate is difficult to rise. The purpose of treatment is to slow down the progress of the disease, and if it is not handled in time, it is likely to cause renal failure, uremia, and so on. Patients with reduced glomerular filtration rate are advised to consult regular hospitals, improve relevant examinations under the guidance of physicians and standardize treatment.