Kidney disease includes renal insufficiency, glomerulonephritis and other diseases. Biochemistry can detect renal failure, but not glomerulonephritis. Biochemistry is the general term for liver function, kidney function, lipids, blood sugar and other laboratory tests. If a patient has renal failure, creatinine and urea nitrogen will be elevated, and biochemistry includes these two items, so biochemistry can detect renal failure. If the patient has glomerulonephritis, the kidney function is normal, so the biochemistry is not able to find out whether the patient has glomerulonephritis. The diagnosis of glomerulonephritis is mainly based on routine urine examination, clinical symptoms, 24-hour urine protein quantification and other comprehensive judgment, such as glomerulonephritis urine routine shows positive urine protein, positive urine occult blood, 24-hour urine protein quantification is elevated, clinical symptoms may include swelling, weakness, poor performance, increased blood pressure and so on. Therefore, biochemistry can detect renal failure, but not glomerulonephritis.