Cerebral white matter degeneration does not affect the patient’s normal life cycle. White matter degeneration mainly refers to the demyelination of the white matter of the brain due to various reasons, usually caused by cerebral arteriosclerosis, chronic cerebral blood supply insufficiency, and other causes are usually seen in toxicity, hereditary, infectious or metabolic diseases. Patients with severe white matter degeneration may experience memory impairment, cognitive decline, diarrhea, and in severe cases, gait retardation, total disorientation, and unsteady walking. The treatment of cerebral leukoaraiosis is mainly to actively prevent cerebral arteriosclerosis, control the risk factors of cerebrovascular, and prevent the aggravation of cerebral leukoaraiosis.