The onset of motor symptoms (such as slow movements and tremors) in Parkinson’s disease may be preceded by a range of non-motor symptoms, including impaired sense of smell, constipation and sleep disturbances. And most of these sleep disorders are rapid eye movement sleep behavior disorder (RBD). RBD is usually the first symptom to appear in degenerative diseases (including Parkinson’s disease, multiple system atrophy, Lewy body dementia, etc.). Skeletal muscle paralysis with dreaming behavior is characteristic of REM. Symptoms are dramatic, with complex, aggressive and even violent movements. In some patients, the symptoms are severe enough to injure the patient and his or her partner. The presence of RBD can be diagnosed by clinical features and polysomnography. patients with RBD have mild motor and autonomic impairment that occurs in conjunction with early neurodegenerative changes. Approximately 50% of patients with spontaneous RBD develop Parkinson’s disease within 10 years. The most common treatment for RBD in patients with Parkinson’s disease is low-dose oral clonazepam at bedtime. Treatment may prevent injury to the patient and partner. As a prodromal symptom of Parkinson’s disease, early diagnosis of RBD and pharmacological interventions are expected to improve the neurodegenerative disease condition.