There is a possibility of nosebleeds with heparin for IVF transplantation. Heparin belongs to anticoagulant drugs, which are mainly used for the prevention and treatment of thromboembolic diseases, and may act on many parts of the coagulation function, resulting in abnormal coagulation function, and nosebleed is also one of the possible adverse reactions during the use of the drug. In addition, heparin treatment may also cause nasal inflammation, resulting in damage to the mucous membrane of the nasal cavity, and vasodilatation may also cause nosebleeds. However, during heparin treatment after IVF transplantation, in addition to the adverse effects of the drug, you should also be alert to nasal inflammation, nasal septum deviation, nasal hemangioma and other problems. Meanwhile, you should also pay attention to nasal care in general, avoid the bad habit of picking your nose, and use physiological sea salt water nasal spray when the nasal cavity is dry. If nosebleed occurs during low molecular heparin treatment for IVF transplantation, it is recommended to review the coagulation function in time and adjust the dosage of medication according to the situation, and at the same time, it is necessary to exclude other causes of nosebleed in the ENT department.