Cold, cough, sputum with blood may be a cold when coughing vigorously caused by mucosal bleeding, may not be a cold, but tuberculosis, lung cancer and other diseases. 1. Mucosal bleeding caused by cold and cough: viral infection can cause congestion and edema of respiratory mucosa during cold and flu, such as coughing vigorously, which may cause small blood vessels of mucosa to rupture and bleed, thus causing the symptom of blood in sputum during cold and cough. 2. Tuberculosis: the clinical manifestations of tuberculosis are often coughing, coughing up sputum, low-grade fever, night sweats, and when the lesions invade the blood vessels, there may be blood in the sputum. When the above symptoms last for more than 2 weeks, one should be highly alert to this disease. 3. Lung cancer: Lung cancer can also be manifested as coughing, coughing up sputum with blood in sputum. If accompanied by systemic symptoms such as emaciation, weight loss and fatigue, one should be highly alert to this disease. Coughing and sputum with blood can be caused by many reasons. It is suggested that patients should consult local hospitals in time, complete the examination, make a clear diagnosis and follow the doctor’s instructions.