Invasive breast cancer grade III indicates that breast cancer cells have stronger proliferation ability, higher malignancy, poorer prognosis, relatively more serious, and need to actively cooperate with treatment. The specific treatment and prognosis are also related to the tumor stage. Early invasive breast cancer grade III without metastasis timely detection, timely surgical resection, further postoperative radiotherapy, regular review, timely detection of metastases, timely treatment, long-term survival is possible. If patients in the middle and late stages are not suitable for surgery and take conservative treatment, the general survival rate is relatively low. It is recommended that patients actively cooperate with the doctor’s treatment, regular postoperative review, maintain a good state of mind and lifestyle habits, in order to prolong the survival period.