Jaundice drainage of cholangiocarcinoma usually recedes in 1 week to 2 weeks, but it is also related to the severity of the disease and the effect of drainage. Early stage of cholangiocarcinoma has no obvious clinical manifestations, while late stage patients may have right upper abdominal pain, abdominal distension, fatigue, lack of appetite, pottery-white stool, jaundice, fever and other manifestations. In the terminal stage, patients may have digestive bleeding, infectious shock, hepatic encephalopathy and other life-threatening symptoms. Clinical manifestations of cholangiocarcinoma vary according to tumor site and size. For extrahepatic or hilar cholangiocarcinoma, jaundice is a more common symptom. Patients who have lost or are not suitable for surgical treatment for the time being can use bile duct drainage to relieve the obstruction of bile drainage. Usually, jaundice subsides in 1 week to 2 weeks after drainage. However, the time for yellowing to subside depends on the effect of drainage, the severity of the disease, and whether it is combined with other diseases that cause jaundice. If liver cancer is suspected but confirmed, it is recommended to go to regular hospitals to evaluate the condition and follow the doctor’s instructions to avoid delaying the condition.