Early manifestations of vitamin D deficiency rickets are neuroexcitability changes, night sweating and serum calcium and phosphorus changes. 1. Neuroexcitability change: Vitamin D deficiency can make the blood free calcium decrease significantly, so that the neuromuscular excitability increases, and the patient has the symptoms of neuroexcitability change such as sleep disturbance, easy to be agitated, tachycardia, or convulsions. 2. Excessive night sweating: Vitamin D deficiency usually leads to excessive night sweating, and the patient may be irritable and wake up suddenly due to the stimulation of sweat when he/she sleeps at night. 3. Changes in serum calcium and phosphorus: It may be due to the calcium and phosphorus metabolism disorders caused by vitamin D deficiency in the body, and the serum calcium and phosphorus may be slightly low in the early stage. It should be reminded that for patients with vitamin D deficiency rickets, it is recommended to go to the hospital in a timely manner, according to the patient’s condition, under the guidance of professional doctors for targeted treatment.