Globulin refers to serum globulin, which is usually not bad if it is 19.6 g/L in young children up to 3 years of age. If it is in other people, it may be a sign of disease and requires prompt medical attention and an active search for the cause. Serum globulin is made up of a mixture of proteins, and under normal circumstances, the serum globulin reference value is between 20 and 40 g/L. Therefore, 19.6g/L is a slight decrease. Determining whether globulin 19.6g/L is bad for a person needs to be determined on a case-by-case basis and cannot be generalized. For young children up to 3 years of age, serum globulin 19.6g/L is normal and usually not harmful. This is mainly because the liver and immune system of normal infants are not fully developed after birth and up to the age of 3 years, so the serum globulin is physiologically low. However, for the rest of the population, a serum globulin of 19.6g/L is below the reference range and may signal disease. It is commonly associated with pathologic factors such as excess adrenocorticotropic hormone, primary hypoglobulinemia, and pharmacologic causes (e.g., 6-mercaptopurine). To summarize, globulin 19.6g/L has certain health risks, and it is necessary to go to the hospital in time for further examination to clarify the specific causes, and cooperate with doctors for active treatment if necessary.