Itchy skin in diabetic patients may be due to neuropathy, dry skin and medications. 1. Neuropathy: Diabetic peripheral neuropathy is one of the chronic complications, caused by metabolic disorders, vascular damage or immune factors, which can lead to a variety of sensations such as numbness, ants or pain in the skin. 2. Dry skin: When diabetes is present, poor glycemic control can affect the autonomic nervous system that innervates the sweat glands, which can lead to abnormal secretion of sweat glands, dry skin, and itchy skin when there is bacterial growth. 3. Drugs: In the process of applying drugs to lower blood sugar, if there is drug allergy, such as taking sulfonylureas such as gliclazide, causing skin allergic reaction, there can be itching or rash. Diabetic patients should actively control blood glucose, take hypoglycemic drugs on time, and if there are other physical symptoms, consult a doctor in a timely manner and follow the doctor’s instructions for treatment.