Uterine fibroids are the most common benign pelvic tumors in women, and they occur in the reproductive age. The incidence of pregnancy-associated uterine fibroids is about 5%. It accounts for 0.3%~7.2% of pregnancies, and the incidence of pregnancy-associated uterine fibroids is on the rise with the delay of childbearing age and the popularity of ultrasound diagnosis. 1, the impact of pregnancy on uterine fibroids 1, the location of fibroids change: with the increase in the size of the pregnant uterus, the location of fibroids also change accordingly, it can be up and down with the extension of the uterine wall or left and right displacement; 2, fibroids increase in size: due to the influence of high levels of estrogen and progesterone during pregnancy and the increase in the blood supply to the uterus, fibroid cells hypertrophy, edema, making fibroids larger and softer, sometimes become flat; 3, fibroids degenerative changes. 3.myoma degeneration and necrosis: due to increased hormone level, mechanical compression and poor blood circulation in the enlarged myoma, it can cause myoma vitreous degeneration, mucus degeneration, fatty degeneration, degeneration and even hemorrhagic necrosis, but red degeneration with hemorrhagic necrosis is more common; 4.tibial torsion: subplasmalemma myoma tibial torsion is not common, but its incidence is significantly higher in pregnancy than other periods. 1. Infertility: whether the fibroid affects conception is related to its growth site, such as myoma in the horn of the uterus can compress the interstitial part of the fallopian tube and prevent the sperm from meeting the egg, leading to infertility; 2. miscarriage and premature birth: the incidence of spontaneous miscarriage in combined pregnancy with fibroids is 2~3 times higher than that without fibroids, reaching 20%~30%, especially in submucosal fibroids, which deform the uterine cavity, and endometrial infection, which is not conducive to fertilization. The endometrial infection is not conducive to the fertilization of the egg, and even if it does, miscarriage may occur due to insufficient endometrial blood supply; larger interstitial fibroids may also cause miscarriage or preterm delivery due to mechanical compression and uterine cavity deformation; 3. In addition, occasional compression by myoma may lead to fetal deformation and FGR; 4. Placental abnormalities: Myoma may cause the adjacent part of the meconium to develop poorly and affect the implantation of the pregnant egg, resulting in placenta praevia or early abruption of the placenta, and the placenta may adhere during delivery and cannot be expelled by itself; 5. The fibroids in the lower part of the uterus or the cervix stay in the pelvic cavity and affect the articulation of the previa and the entry into the pelvis, resulting in abnormal previa and abnormal fetal position, which hinders normal delivery. During delivery, the fibroids make the uterus contraction malfunction, causing primary or secondary uterine contraction weakness, resulting in prolonged labor; 6.Postpartum hemorrhage: due to the presence of fibroids, which hinder uterine contraction, especially when there are submucosal fibroids, or when the placenta is attached to the surface of the fibroids, placental adhesions or even implantation can easily occur, resulting in significantly increased postpartum hemorrhage; 7.Uterine torsion: if there is a fibroid on one side of the uterine body, with the pregnancy and uterus, the uterus can be twisted. The uterus may twist with the softening of the cervix in pregnancy, resulting in sudden severe abdominal pain and shock in severe cases; 8, puerperal infection: poor uterine regeneration, poor drainage of malignant fluid or prolapse of submucosal fibroids may induce puerperal infection. If there is no symptom during pregnancy, no special treatment is needed, and regular prenatal checkup is sufficient. If the fibroid develops red degeneration, it can almost always be relieved by palliative treatment without surgery, no matter in pregnancy or puerperium. If subplasmalemmal leiomyosarcoma becomes twisted and conservative treatment is ineffective, surgical intervention is indicated. If the myoma is embedded in the pelvic cavity and interferes with the continuation of pregnancy, or if the myoma compresses the adjacent organs and serious symptoms appear, surgical treatment is indicated. Whether or not to terminate the pregnancy at the time of surgery should be determined by the patient’s specific situation. In late pregnancy, the mode of delivery should be determined according to the size and location of the fibroid, the fetus and the mother’s specific situation. During labor, if abnormal fetal position, abnormal labor force, compression and obstruction, or difficulty in lowering the fetal dewlap occur due to myoma, cesarean section should be performed in time to end the labor, and uterine bleeding should be prevented during and after the operation. Whether to remove the fibroid or uterus at the same time during cesarean delivery should also depend on the size and location of the fibroid and the patient’s condition. If the submucosal myoma is discharged into the vagina during vaginal delivery, the myoma with the tip can be removed vaginally after delivery of the fetus, but care should be taken not to cut through the uterine wall. After delivery, care should be taken to prevent bleeding and infection.