If liver nodule of 2cm is found 1 month after liver cancer surgery, ultrasound, CT, pathological biopsy, AFP and other tests should be performed to clarify the nature of the disease, and then surgical and interventional treatments should be chosen according to the situation. Post-operative liver cancer patients should be regularly monitored, reviewed and followed up, so that patients with early detection of metastasis or recurrence can receive early treatment and thus improve their prognosis. If 2cm liver nodules are found one month after liver cancer surgery, patients should go to regular hospitals to complete relevant examinations in time, including serum AFP, ultrasound, CT, MRI and pathological biopsy, etc., so as to clarify the nature of the disease and its condition (quantity, size, etc.). If the tumor is malignant, mostly intrahepatic metastases of hepatocellular carcinoma or neoplastic tumors, the patient’s survival can be prolonged by choosing the treatment plan according to the situation, including immunosuppression, re-surgical resection, ablation, radiotherapy, transhepatic artery cannulation chemoembolization, and so on. Therefore, it is recommended that patients follow the doctor’s instructions for further definitive examination to determine the specific location and nature of the nodule, etc., and decide the next treatment plan.