A 2-year-old baby always wakes up at 2-3 o’clock in the middle of the night, which may be related to cold and heat, indigestion, lack of calcium in the body or pinworms and other reasons. 1. Environmental factors: when the baby’s living environment is hot and stuffy or cold at night, it may wake up in the middle of the night, it is recommended to ensure that the home environment is comfortable. 2. Indigestion: babies eat too much or too little at night can cause abdominal discomfort, indigestion symptoms such as abdominal pain, due to pain babies wake up at night, crying. 3. Calcium deficiency: when the baby’s body is deficient in calcium, it can cause sleep disturbance, night crying or loss of appetite and other manifestations, parents should pay attention to the child’s physical development in a timely manner. 4. Pinworms: the child’s fingers are contaminated with pinworm eggs, eggs through the mouth into the body can cause self-infection, resulting in gastrointestinal irritation symptoms such as abdominal pain, diarrhea, but also see the night terrors, insomnia or anxiety and other symptoms. The baby woke up frequently at night, need to go to the hospital specialist consultation, identify the cause of the disease, symptomatic treatment.