Many patients with varicose veins in the lower extremities ask in the clinic, “I don’t want to operate for the time being, can I take some medicine? It can be estimated that the incidence of varicose veins in lower extremities is more than 10%, and there are more than 100 million patients in China, and the largest vascular surgery conference in China, CEC, has 3000 participants, including many related disciplines such as nephrology, nursing staff, postgraduate students, etc. Assuming that each person does 500 varicose vein surgeries per year, this is a very extreme quantity, full calculation The annual surgery volume of 1.5 million, and then the general surgery, orthopedics and other doctors who can do varicose veins surgery are counted, then there are more than 90 million people who do not operate, so there are very many patients who need this, I specifically organized a varicose vein drug treatment related content to do a brief science popularization. If the varicose veins are mild, surgery is not necessary, or if the patient is busy and does not have time for surgery, medication and compression therapy can slow down the development of varicose veins, and surgery may not be necessary in the future. 1.When do I need to take medication? There are symptoms, complications blood clots, ulcers, bleeding, eczema. Early varicose veins have no uncomfortable symptoms, so pay attention to avoid standing and sitting for a long time, elevate the sick leg and wear elastic stockings to effectively control varicose veins. In moderate varicose veins and above, leg pain, heaviness, cramping and itching will gradually appear, which can be improved by taking vein-active drugs. Many patients will also have the experience that their legs are relaxed after taking the drugs and their legs do not sink after walking for a long time. Complications such as blood clots, ulcers, bleeding, eczema can occur when varicose is more serious, and medication can be used as an adjunct before and after surgery. 2.What are the medications? What is the principle? In order to be easy to understand, I summarize it as four vajra and two guardians. Patients in all stages of chronic venous disease need to be treated with medication. Drug therapy can effectively reduce the clinical signs and symptoms of patients. The four vassals are venoactive drugs (VADs): their common mechanism of action is to increase venous tone, reduce vascular permeability, promote lymphatic and venous reflux and improve calf muscle pump function. They are indicated for patients in any stage of varicose veins and can also be used in combination with sclerotherapy, surgery and/or compression therapy. Heptaoside: Heptaoside is represented by Mai Zhi Ling, an extract of horse chestnut seeds, which has the effect of reducing capillary permeability, increasing venous tone, promoting venous blood return and reducing edema. Widely used at home and abroad, its efficacy is precise. Coumarins: Coumarins are derived from the extract of herbaceous rhinoceros plant. The trade name of coumarin-M, also known as herbaceous rhinoceros flow infusion tablets, is to reduce edema effectively by reducing capillary permeability, promoting blood circulation and increasing blood flow, and promoting lymphatic reflux. Flavonoids: The main component of flavonoids is Diosmin, one of which is a micronized purified flavonoid, represented by Avalanche, containing 450
mg of diosmin and 50 mg of hesperidin, with a small intestinal absorption rate twice that of the non-microfilmed flavonoids. It has a unique intravenous anti-inflammatory effect and inhibits the interaction between leukocytes and vascular endothelial cells, which can slow down the disease process with long-term application. The other category is common diosmin, a non-particulate drug, which is also widely used by domestic doctors and has certain efficacy in relieving varicose vein symptoms. Calcium hydroxybenzenesulfonate acts on the endothelial cell layer and basal layer of capillary vessels, regulates and improves capillary permeability and flexibility, increases the resistance of capillary walls, reduces their permeability, has an activating effect on the lymphatic circulation system, reduces blood and plasma viscosity, decreases platelet hyperaggregation and lowers plasma viscosity. Full
0.5g (2 tablets) once, 2 times a day, for 1-3 weeks. Subsequent doses of 0.5g to 1.0g (2-4 tablets) daily to consolidate the efficacy. The two major nursing methods are the antithrombotic drugs and anti-inflammatory drugs to be combined when varicose veins have complications such as thrombophlebitis and ulcers. Anti-thrombotic drugs include classical warfarin, aspirin, rivaroxaban, and also blood-stasis activating herbs: blood-stasis activating and softening herbs have better treatment effect on skin damage. Anti-inflammatory drugs also include non-steroidal anti-inflammatory drugs: for the relapse and active period of seborrheic scleroderma, it has good anti-inflammatory and anti-swelling and pain-relieving effects. 3.Can medication cure varicose veins? Improve, not cure. 4.Is there any topical medicine? Can varicose veins be reduced by rubbing it on the varicose veins? There is no prescription medicine, but there is a commercial one, the effect, huh 5.How long do I need to take it? Usually you don’t need to take it for a long time. Severe varicose veins with ulcers, eczema, skin sclerosis using vein active drugs adhere to at least
3-6 months, can significantly improve the clinical symptoms. 6.What are the side effects? Gastrointestinal reactions are the most common, some patients will have nausea, vomiting, anorexia and other symptoms after taking it, you can consider changing the drug. In addition, abstinence and diosmin tablets should be taken before meals. Other side effects include bleeding, allergies, and rashes are relatively rare and need to be discontinued when they occur.