Total serum protein, as the name suggests, is the total protein in the serum, and is one of the liver function tests, which is the total amount of all proteins contained in the serum. More than 90% of total serum protein is synthesized by the liver, so total serum protein and albumin are very important indicators of the synthesis function of the human liver. An increase or decrease in total serum protein is often indicative of liver disease or other disorders.