Some of the triple-negative breast cancer chemotherapy may need to be done 16 times, which is in line with the requirements of the treatment. The specific number of treatments needs to be decided according to the patient’s condition, physical condition and so on, and the patient should follow the doctor’s instructions for a full course of treatment in sufficient quantity. Triple-negative breast cancer means that after immunohistochemical examination, women with breast cancer are negative for estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2. Triple-negative breast cancer has a relatively high recurrence rate and requires a sufficient number of chemotherapy treatments. Anthracycline drugs such as epirubicin are commonly used, combined with cyclophosphamide, or paclitaxel chemotherapeutic agents such as docetaxel and paclitaxel, usually in a cycle of 21 days. For early stage triple-negative breast cancer without metastasis, generally there is no need to do 16 cycles of chemotherapy. For patients with advanced stage considering localized lymphatic metastasis, or peripheral nerve invasion and cancer embolism in the vasculature, it may be necessary to do 16 rounds of chemotherapy in order to improve the patient’s life treatment and prolong the survival period. The exact number of chemotherapy sessions should be determined by the patient’s condition, physical status, and treatment effect. During the treatment period, patients may have reactions of bone marrow suppression such as fatigue, nausea, vomiting, etc. It is necessary to pay attention to monitoring the changes of blood routine, liver and kidney function indexes, and in case of serious side effects, it is necessary to consult a doctor in time for treatment and adjust the treatment plan if necessary. Early detection, diagnosis and treatment of breast cancer patients can effectively improve the prognosis of the disease. It is suggested that patients should consult the doctor in time and actively cooperate with the doctor’s treatment, who will formulate an effective treatment plan according to the condition in order to promote the recovery of the disease.