The performance of depression 1, the degree of depressed state of mind varies, can range from mildly poor state of mind to sadness, pessimism, despair. Patients feel heavy, life is meaningless, happy, depressed, spending days like years, painful, and can not allocate themselves. Some patients may also appear anxious, easily agitated, nervous and restless. 2, negative pessimism: very painful, pessimistic, despair, feel that life is a burden, not worth staying, to die for relief, may produce strong suicidal thoughts and behavior. 3.Somatic or biological symptoms: depressed patients often have biological symptoms such as loss of appetite, weight loss, sleep disorders, low sexual function and diurnal fluctuations in mood, which are very common but not in every case. 4, loss of appetite, weight loss: most patients have poor appetite, poor appetite symptoms, delicious food is no longer tempting, patients do not think about tea and food or tasteless, often accompanied by weight loss. 5. Sleep disorder: The typical sleep disorder is early awakening, 2 to 3 hours earlier than usual, not going back to sleep after waking up, and falling into a sad atmosphere. 6.Loss of interest is one of the common symptoms of depressed patients. Loss of enthusiasm and pleasure in life and work, and loss of interest in everything. 7.Loss of energy, fatigue and weakness, difficulty in washing, dressing and other trivial things in life, and inability to cope. Patients often use the words “mental breakdown” and “deflated ball” to describe their condition. 8. Low self-evaluation: Patients tend to excessively depreciate their own abilities, and look at their present, past and future in a critical, negative and negative manner, saying that they are useless and their future is dark. Strong feelings of self-blame, guilt, uselessness, worthlessness, helplessness, and in severe cases, self-guilt and suspicion may appear. 9.Patients show significant, persistent and general depressive state, difficulty in concentration, memory loss, brain dullness, closed-mindedness, and slow action, but some patients show restlessness, anxiety, nervousness and agitation. 10. Diurnal variation: The patient’s state of mind has a diurnal variation of heavy day and light night. Early in the morning or morning into the state of mind of the low tide, afternoon or evening gradually see improvement, can carry on a short conversation and meal. The incidence of diurnal variation is about 50%.