What medication to take for heavy menstruation in a 50 year old woman needs to be chosen according to the cause of the disease. If it is perimenopausal syndrome, you can take estrogenic drugs, hemostatic drugs and so on. If it is uterine fibroids, endometrial cancer and other diseases, taking medicine alone is useless, need to take surgical treatment. 1. Perimenopausal syndrome: 50-year-old women with heavy menstruation are considered to have perimenopausal syndrome, and patients can take oral estrogen, such as estradiol, estradiol valerate, etc., under the guidance of doctors. If the bleeding is heavy, you can also take hemostatic drugs such as tranexamic acid as prescribed by the doctor. 2. Uterine fibroids: For 50-year-old women with heavy menstruation caused by uterine fibroids, surgical treatment, such as myomectomy, or hysterectomy if necessary, can be considered. 3. Endometrial cancer: heavy menstruation of 50-year-old women can not be ruled out due to endometrial cancer, which needs timely surgical treatment after diagnosis, such as total uterine bilateral tubal and ovary resection, radical hysterectomy, etc., and cooperate with radiotherapy and chemotherapy after operation to enhance the curative effect. The causes of heavy menstruation in 50-year-old women are many, and it is recommended that patients seek medical examination to clarify the diagnosis, and it is not advisable to use medication on their own.