Diabetic patients with eczema all over the body, mainly to drug treatment, it is recommended that the treatment under the guidance of the doctor. First of all, the patient’s blood sugar should be controlled, because eczema patients with poor blood sugar control, may be secondary to bacterial infection as well as fungal infection, for the healing of eczema will be more unfavorable, so blood sugar control is the first step. The first step is to control the blood sugar. You can take oral glimepiride, acarbose and other medications as prescribed by the doctor. Secondly, topical medication should be chosen according to the severity of the disease and age. Calcium-modulated neural phosphatase inhibitors (e.g. tacrolimus ointment, pimecrolimus cream) have better efficacy. At the same time of medication, patients should have a reasonable nutritional diet, it is not recommended to eat foods with high sugar content, it is recommended that patients should have a light diet, it is not recommended to eat greasy food, it is advisable to eat a reasonable diet, pay attention to rest. Patients with diabetic generalized eczema should not take medication on their own, and need to go to the hospital in time, under the guidance of the doctor.