Warts on the hands are caused by infection of the skin with the human papilloma virus, which is a benign epidermal growth. The virus can be transmitted through direct or indirect contact, so when the body’s immune system is weakened or the skin is damaged or rubbed, a rash of warts may appear on the area. The rash may initially be a small, rough papule that gradually increases in size, with significant keratinization and a hard texture. There is no obvious itching or pain associated with warts, which can be treated with liquid nitrogen freezing, laser, or electrocautery. The reason for the warts on the hands is because of the infection of human papilloma virus, so actively seek physical therapy and give topical antiviral drugs to effectively inhibit and control the occurrence of common warts.