The quadruple vaccine is similar to the free triple vaccine in that it can prevent whooping cough, diphtheria and tetanus, so you can choose the type of vaccine according to your own needs and after consulting with your doctor. 1. Quadruple vaccine: it can effectively prevent diphtheria, tetanus and whooping cough, as well as Haemophilus influenzae type B infections, with a comprehensive preventive effect, but the quadruple vaccine is paid, belonging to a national category II vaccine, which belongs to the type of vaccine for voluntary vaccination, so that parents can decide whether or not they need to be vaccinated according to their financial situation and their children’s condition. 2. Free vaccines: can effectively prevent diphtheria; tetanus and whooping cough these three diseases, belong to the triple vaccine, is a free, but also the state mandatory vaccination. In addition, the more common adverse reactions to vaccination are redness, swelling, pain and nodules at the site of vaccination, which may cause fever, and patients with acute diseases should not be vaccinated. In addition, there are certain contraindications to vaccination, and it is recommended that parents consult with a specialist before inoculating their children.