The Chinese name of PPI is proton pump inhibitor and contains varieties such as omeprazole, esomeprazole magnesium enteric coated tablets, pantoprazole, lansoprazole tablets, rabeprazole sodium and eprazole enteric coated tablets. Proton pump inhibitors inhibit the secretion of basal gastric acid and acid secretion caused by histamine, acetylcholine, gastrin, and feeding a variety of stimuli by specifically acting on H-K-ATPase on the tubular vesicle membrane in the gastric wall cells, which irreversibly binds to the proton pump, rendering it inactive. Proton pump inhibitors are widely used in the treatment of acute and chronic acid-related diseases of the digestive system, including gastroesophageal reflux disease, Dro-Ai syndrome, peptic ulcer, upper gastrointestinal bleeding and related diseases, eradication of Helicobacter pylori infection, as well as prevention and treatment of stress gastric mucosal lesions, and upper gastrointestinal diseases after tumor chemotherapy.