Regarding the treatment of vasculitis, stem cell transplantation is currently one of the most advanced medical technologies in the world. Stem cell transplantation involves implanting stem cells into ischemic tissues to promote the generation of new blood vessels and improve blood supply. This type of treatment is suitable for chronic ischemic diseases of the lower limbs caused by various reasons, such as vasculitis, diabetic foot, etc., and can be chosen when the results of conservative treatments are unsatisfactory. Stem cell transplantation is mostly autologous, there is no immune rejection reaction, the long-term effect is obvious, and this type of surgery is repeatable, can be used several times to achieve satisfactory therapeutic effect, suitable for middle-aged and elderly patients. If the diagnosis of vasculitis is confirmed, it is recommended that standardized treatment be carried out as soon as possible to reduce the adverse effects of the disease.