In the clinic, there are two kinds of drugs for rapid thrombolysis: urokinase and alteplase, but more often alteplase is chosen, which is relatively more effective and safer. In the clinic, some areas are not well-developed medical equipment, may also use urokinase for thrombolysis, but the effect of urokinase is not as good as alteplase, and may also induce bleeding, more unfavorable for patients, so the maximum possible to ensure the thrombolysis of alteplase. This is a better effect. The dose of alteplase application and the time of application have certain requirements. Therefore, the dosage of alteplase must be decided according to the patient’s availability and the specific situation at the time. Because sometimes abnormal reactions such as bleeding may be induced, and not all thrombi can be dissolved, these need clear guidance to improve the examination and early treatment is more beneficial.