Pain in the middle of chest when drinking water may be related to excessive secretion of gastric acid, esophageal tumor and chronic gastritis. 1. Excessive secretion of gastric acid: When gastric acid is secreted excessively, when gastric reflux occurs, the stimulation of gastric acid will cause congestion and edema of esophageal mucosa, and even esophagitis, which will lead to the symptom of pain in the middle of chest when drinking water. 2. Esophageal tumor: when patients suffer from esophageal tumor, the normal peristaltic function of the esophagus will be damaged when the esophagus is narrowed or ulcerated due to tumor compression, so that the pain in the middle of the chest and distension will occur when drinking water. 3. Chronic gastritis: chronic inflammation of gastric mucosa caused by various reasons such as Helicobacter pylori infection, drug stimulation, stimulation of digestive juices, etc., which may be accompanied by dull or burning pain in the middle of chest and upper abdomen, often with nausea, acid reflux, belching (burping) and other discomforts, and may be manifested as pain in the middle of chest when drinking water. Drinking water pain in the middle of the chest may also have other causes, it is recommended to appear to go to the hospital for examination, identify the causes under the guidance of the doctor treatment.