Diarrhea with anal pain is considered to be diarrhea-induced anal pain, which can be handled through physical therapy, medication, and treatment of the primary disease. Diarrhea is a common accompanying symptom of digestive system diseases, and the increased frequency of bowel movements will cause anal swelling and congestion, thus causing anal pain. 1. Physical therapy: first of all, keep the anal skin clean and hygienic, more flow of warm water for rinsing, while increasing the amount of water to promote metabolism. 2. Drug treatment: you can apply zinc oxide ointment for local protection, if there is infection, you can use erythromycin ointment, fusidic acid cream and other drugs for treatment. 3. Treatment of primary diseases: at the same time, further examination of stool routine, blood routine and so on. If the diarrhea is caused by enteritis, you should choose to take sensitive antibiotics such as norfloxacin and so on, with the relief of intestinal spasm of drugs such as belladonna tablets, scopolamine and so on, at the same time with montelukast and other medicines, adsorption of antidiarrheal, symptomatic treatment. Diarrhea with anal pain, it is recommended to actively seek medical attention, drugs need to be used under the guidance of a professional doctor.