What is the cause of impaired glucose tolerance

Impaired glucose tolerance refers to a decrease in the body’s ability to tolerate glucose. After 2 hours of oral intake of a certain amount of glucose (82.5 g with water or 75 g without water), the blood glucose value exceeds the normal value of 7.8 mmol/L but still does not reach 11.1 mmol/L or the fasting blood glucose is high, between 6.2 and 7.0 mmol/L. It is an intermediate state between diabetics and normal people.

Impaired glucose tolerance is closely related to diet and exercise. Hypertension, obesity, abnormal lipid metabolism, and insulin resistance are important risk factors for abnormal glucose tolerance, and the important causes of these factors are closely related to diet and lack of exercise. In today’s rapidly developing world, material life is getting richer and richer, meat and excessive fats become indispensable food on the table. Coupled with excessive intake of carbohydrates lead to excess calories, it is easy to produce obesity. Obesity is the root cause of abnormal glucose metabolism, insulin resistance and abnormal lipid metabolism. In addition, the development of transportation nowadays has led to a serious lack of exercise, which can increase the rate of impaired glucose tolerance.