Azithromycin side effects and adverse reactions are commonly seen in the gastrointestinal system, in addition to liver damage, nervous system, cardiovascular system, and allergic reactions. 1. gastrointestinal reactions, such as nausea and vomiting, diarrhea and abdominal pain. 2. Liver damage, such as obstructive jaundice, elevated liver aminotransferase AST and ALT. 3. Neurologic injuries, such as headache and drowsiness. 4. Cardiovascular events, such as Q-T interval prolongation, arrhythmia, etc. 5. allergic reactions, such as rash, pruritus, photosensitivity reaction and angioedema, etc. 6. Ototoxicity, anxiety, etc. Azithromycin belongs to macrolide antibacterial drugs, through the inhibition of bacterial protein synthesis to play an antibacterial effect, can be used for acute pharyngitis caused by Streptococcus pyogenes, acute tonsillitis, Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae due to community-acquired pneumonia, sensitive bacteria caused by the skin and soft tissue infections, such as the treatment. Note that azithromycin is contraindicated in patients with a history of cholestatic jaundice and hepatic insufficiency. Patients should use it under the guidance of a professional physician and strictly comply with medical advice.