Fibromyalgia syndrome is a non-articular disease that is characterized by pain and stiffness in many muscles throughout the body, accompanied by fatigue, coldness, insomnia and other symptoms. Its prevalence is about 2%, with 3.4% for women and 0.5% for men. The clinical manifestations of the disease are diverse, but the “characteristic” symptom is chronic widespread muscle pain, mostly accompanied by skin tenderness, sometimes mild and sometimes severe. 13% of patients have widespread muscle pain, 43% have limited pain, the neck, chest, lower back, scapula and pelvic muscles are the most common. 81% of patients have more than 11 pressure points. pressure points, with more pressure points in women than men. Minor injuries, cold, poor sleep, depression, and excessive stress can cause pain episodes, which can be aggravated by humid weather and low air pressure. 90% of patients often have sleep disturbances and mental disturbances, and more than half of patients may have severe fatigue or even be unable to work. Morning stiffness is seen in about the majority of patients and its severity may be related to poor sleep and mental depression. Other manifestations may include headache, chest pain, dizziness, sensory abnormalities, dyspnea, depression and anxiety. Patients often report joint swelling without objective signs.