Whether urine routine red blood cells weak positive is serious or not is related to the cause, if it is caused by physiological reasons such as female menstruation, strenuous exercise, it is not serious. If it is caused by pathological factors such as urinary tract infection, urinary stones, etc., it is generally not serious. If it is caused by malignant tumors of the urinary system such as bladder cancer, kidney cancer, etc., it is more serious. Urine specimen taken during women’s menstruation may show weak positive result because of contamination, which needs to be rechecked after the end of menstruation. Healthy people who exercise strenuously may also show weak positive result of urinary erythrocytes, which can be improved after resting, and it is not serious at this time. Generally, weakly positive urine erythrocytes can be seen when suffering from urinary tract infection (such as pyelonephritis, cystitis, etc.) and urinary stones (such as ureteral stones, kidney stones, etc.), and the disease can be improved after anti-infective and lithotripsy treatments, which is not serious. If there are tumors in the urinary system, such as bladder cancer, kidney cancer and other diseases, there will also be weakly positive urine erythrocytes in the early stage, and the disease is generally more serious. When urinary red blood cells are weakly positive, it is necessary to further examine under the guidance of a doctor to clarify the cause and then follow the doctor’s instructions to standardize the treatment.