Although obesity is not a disease, it is a predisposing factor for many medical conditions. Here today is a brief introduction to the relationship between obesity and arthritis. Some readers may think it is obvious that the legs have to bear so much weight. It is easy to develop arthritis. However, obesity may cause endocrine disorders that can lead to arthritis. Arthritis is a multifactorial disease. Mechanical, genetic, and biochemical factors are all important factors in the development of arthritis. Studies have shown that knee arthritis is associated with obesity up to 70.73%. The increased weight mass of obese people leads to increased habit sisf and, in turn, uneven force on the surface of the knee joint, accelerating cartilage loss and bone flab formation, leading to the development of arthritis. At the same time, obesity increases the risk of arthritis of the hand. The correlation between obesity and non-weight-bearing arthritis is difficult to explain, and obesity is accompanied by metabolic alterations. For example, reduced glucose tolerance, hyperuricemia and altered lipid metabolism may affect the metabolism of articular cartilage. In addition, adipose tissue secretes a large number of adipokines such as leptin, adiponectin, visceral adiponectin and resistin, which contribute to arthritis in terms of cartilage degeneration and inflammation development. Imagine that arthritis is induced due to high body weight-like. As a result, it is impossible to increase calorie consumption. But the amount of food is not well controlled. What a terrible vicious circle! The obesity induced disease is like drawing a prison, trapping the patient firmly. If you want to break out of the dilemma, you must strictly control your diet. In case the calorie intake is not controlled by accident, a few days of effort may be lost. In some patients, the arthritis is significantly better after successful weight loss. Arthritis is also an invisible shackle left by obesity. Obese patients, before the disease appears to be prevented, pay attention to their health and stay away from obesity.