The liquefaction of fibroids is mainly due to the compression of fibroids, which reduces the blood circulation of the envelope and causes the fibroids to liquefy. If the liquefaction occurs in small fibroids, it is not harmful to the body, but it must be reviewed regularly, for example, once every 3 months by ultrasound. If the liquefaction of relatively large fibroids occurs, attention must be paid to avoid infection, because the poor circulation of the pericardium may cause local necrosis, which may lead to infection, and it is recommended to take oral antibiotics for treatment and to closely observe the changes clinically, and if necessary, surgery is recommended.