Do I have to undergo sterilization if I am found to be positive in the H. pylori test? Not necessarily. Currently, eradication therapy is considered necessary in the following cases 1. Patients with peptic ulcer. 2.Patients with early gastric cancer after surgery. 3.Patients with lymphoma of gastric mucosa-associated lymphoid tissue. 4, Patients with chronic gastritis combined with erosion or moderate to severe atrophy or moderate to severe enterosis or mild to moderate heterogeneous hyperplasia. In addition, anti-Helicobacter pylori treatment is also supported in some functional dyspepsia (those with poor conventional treatment) and those with a family history of gastric cancer.