Sore throat with phlegm, considered to be suffering from acute pharyngitis, acute epiglottitis, acute tonsillitis and other diseases caused. According to different causes, you can take different medications as prescribed by the doctor, for example, pharyngitis patients can take oral amoxicillin capsules, acute epiglottitis patients can take oral levofloxacin tablets, tonsillitis patients can take oral cefuroxime sodium tablets and other drugs. 1. Acute pharyngitis: If you suffer from pharyngitis, the sore throat with phlegm may be accompanied by burning sensation in the throat and other symptoms. If pharyngitis is induced by bacterial infections such as hemolytic streptococcus, antibiotics such as cefuroxime sodium tablets and amoxicillin capsules can be taken orally for anti-infection treatment to relieve symptoms. 2. Acute epiglottitis: If acute epiglottitis is induced by bacterial infections such as Streptococcus pneumoniae and Staphylococcus aureus, resulting in sore throat and phlegm, patients can take oral amoxicillin capsules, levofloxacin tablets and other antibiotics to achieve antiseptic and anti-inflammatory effects. 3. Acute tonsillitis: patients may have fever, pharynx with foreign body sensation and other symptoms. If viral infection induced tonsillitis, resulting in patients with a sore throat and phlegm, generally do not need to be treated, usually the condition can be self-healing; if the bacterial infection induced tonsillitis, the patient can take penicillin, cefaclor and other antibiotic drugs treatment. It is recommended that patients with sore throats and phlegm go to the hospital for treatment, and take appropriate oral medication as prescribed by the doctor after clarifying the cause of the illness.