The normal value of indirect bilirubin is 1.71-13.68μmoL/L, if the value is 22μmol/L, it is high, and the severity of its degree, need to consider the physiological and pathological factors, the pathological is more serious. 1. Physiological: Under physiological conditions, transient elevation may occur during strenuous exercise, heavy drinking, and excessive fatigue, and can be restored by self-regulation after rest. 2. Pathological: such as viral hepatitis, resulting in damage to liver cells; hemolytic jaundice, excessive destruction of red blood cells, resulting in high indirect bilirubin, these cases need to go to the hospital in a timely manner, combined with other test results, to determine the cause of the disease, under the guidance of the doctor for targeted treatment. Daily should develop good living habits, three regular meals, supplement fresh vegetables and fruits, quit smoking, quit drinking; keep in a good mood; regular life, avoid staying up late, enhance exercise, improve physical fitness.