The most effective measures to expel sputum in patients with bronchiectasis are as follows: 1. In addition to oral expectorant and cough suppressant medications, nebulized inhalation therapy should be chosen, usually budesonide nebulizer combined with chymotrypsin and ambroxol, which can promote sputum dilution and thus expel sputum. 2. Bronchodilator medications, such as salbutamol nebulizer, terbutaline nebulizer, ipratropium bromide nebulizer, should be used as necessary to dilate the airways and facilitate sputum expulsion. 3. 3. If necessary, you can choose bronchial fiber endoscopy to flush out the sputum by saline flushing of the airway, and you can also choose aspirator to suck out the sputum in the airway.