Whether or not post-transplant exhaustion can interfere with fertilization depends on the patient’s condition. Under normal circumstances, bowel movements can lead to anal exhaustion, which is normal 3-5 times a day. If the patient does not have special conditions such as increased exhaustion or diarrhea, the exhaust will not affect the fertilization of the egg. If the patient has inflammatory bowel disease or other causes of hyperactive bowel movements, the fertilized egg may be affected by increased exhaustion, diarrhea and abdominal pain. Because the female intestine is adjacent to the uterus, increased intestinal peristalsis can stimulate the uterus and cause uterine contractions. If the contraction of the uterus strengthens, it will affect the normal fertilization of the fertilized egg and may lead to failure of fertilization and biochemical pregnancy, so active treatment is necessary in this case.