The whole body itchy at night may be hives, eczema, scabies and other diseases. 1. Urticaria: patients with urticaria will usually suddenly self-conscious itchy skin, and the emergence of different sizes of wind, can be intermittent or daily attacks, some patients will be attacked at night, resulting in the whole body itchy. The cause may be related to infection, autoimmune, mental and other factors. 2. Eczema: Eczema patients will appear red spots, pimples and intense itching, exacerbated at night. The cause may be due to immune abnormalities, heredity and other factors. 3. Scabies: Scabies patients mainly show papules, pimples and blisters, accompanied by intense itching, and the symptoms will be more serious at night because the scabies insect is more active at night. The formation of scabies is mostly related to the infection of the skin by the human scabies mite. There are many reasons for the strange itching all over the body at night, and patients are advised to seek medical examination to clarify the cause.