Taking anti-inflammatory drugs can generally eat horse hooves, and will not reduce the effect of anti-inflammatory drugs; however, it is not recommended to eat horse hooves when the patient has obvious gastrointestinal symptoms.
Anti-inflammatory drugs usually refers to antibiotics, mainly used to treat bacterial infections; such as levofloxacin, cefixime and other antibiotics. Horseshoes are a food and do not have medicinal value, nor do they detoxify antibiotics. Therefore, it is generally okay to eat horseshoes when taking antibiotics.
However, it should be noted that some bacterial infectious diseases may be accompanied by obvious gastrointestinal symptoms, such as acute gastroenteritis and some bacterial pneumonia. Although hoofs do not affect the effectiveness of antibiotics in these cases, they may increase the burden on the gastrointestinal tract (containing 1.1g/100g of dietary fiber).