Severe pulmonary hypertension may be caused by heart disease, lung disease, etc. Generally, the prognosis is not good and it is difficult to be cured, but it can be relieved by medication and surgery. 1. Drug treatment: you can use pulmonary vasodilators such as calcium channel blockers such as nifedipine, prostaglandin drugs such as iloprost, etc. If there is a combination of right heart insufficiency or edema, you can use diuretics such as furosemide, etc., and digoxin can be used in patients with severe right heart insufficiency. 2. Surgical treatment: If the effect of drug treatment is not good, surgical treatment can be taken to carry out double lung transplantation or heart-lung transplantation, which is generally not used because surgical treatment may lead to the death of the patient during anesthesia and surgery. If you suffer from severe pulmonary hypertension, you should seek active medical treatment, and specific drugs should be used under the guidance of a doctor.