Patchy low-density shadow with fuzzy border seen in spleen means that there are cysts, abscesses, hemangiomas and other occupations in the spleen. Since the contents of these masses are mostly liquid and less dense than the parenchymal tissues of the spleen, patchy low-density shadow with fuzzy border is seen. 1. Cysts: Splenic cysts can be divided into parasitic and non-parasitic cysts. Non-parasitic cysts may be caused by secondary factors such as trauma, infarction, hemorrhage, etc., or congenital. 2. Abscess: Bacterial infection may invade the spleen, when mononuclear-phagocytic cells and fibrous tissue surround the infected foci, splenic abscess may appear, usually there will be chills and high fever in clinical manifestations. 3. Hemangioma: the mechanism of hemangioma is not clear, but when hemangioma occurs in spleen, if the volume is small, it is not necessary to deal with it. If the volume is large, it can be treated surgically to reduce the possibility of hemangioma rupture and bleeding. If the spleen sees patchy low-density shadow and fuzzy boundary, it is recommended that the patient should go to the regular hospital for further examination, make a clear diagnosis, and standardize the treatment under the guidance of the physician, so as to avoid delaying the condition.