Whether or not you can stop using urethane particles after the creatinine is reduced to normal is recommended to strictly follow the doctor’s instructions, if the patient is only taking urethane particles for high creatinine, it is possible to consider stopping, but if other abnormalities exist, it is generally not possible to stop using. Uremic acid granules have the efficacy of clearing turbidities through the bowels, strengthening the spleen and inducing dampness, activating blood circulation and removing blood stasis. It is used for chronic renal failure, azotemia stage and early uremia, Chinese medicine identification of spleen deficiency and dampness and spleen deficiency and blood stasis. It can reduce creatinine and urea nitrogen, stabilize renal function and delay dialysis time. It also has a certain effect on improving renal anemia, raising blood calcium and lowering blood phosphorus. If patients take urethane particles to reduce creatinine, when the creatinine is reduced to normal, the drug can usually be stopped. However, if the patient has other medical conditions, he or she may need to continue to take urethane granules. If you need to stop the drug or increase or decrease the dosage need to be under the guidance of a doctor, the patient can not arbitrarily decide on their own.