Grape powder is recommended to eat 30 minutes after three meals is best, but is not recommended to take before bedtime, because the grape powder has the effect of excitation of the nerve center, so eating grape powder before bedtime will have poor sleep quality, insomnia and dreaming and so on. In addition, it is not recommended to take grape powder on an empty stomach, because grape powder is an acidic ingredient, such as long-term fasting will damage and burn the gastric mucosa, excessive secretion of gastric acid will cause a certain amount of stimulation of the gastric mucosa, long-term fasting grape powder will cause acid reflux, which triggered gastric ulcers. Therefore, the best time to take grape powder is 30 minutes after three meals, but it is not recommended to take grape powder for a long time, because long-term use of grape powder will increase the body’s glucose, which can lead to abnormal glucose tolerance or impaired fasting glucose, so it is recommended that short-term use can be.