Orbital swelling and pain accompanied by migraine head swelling and pain should be based on the specific cause of the medication. The main causes are sleep deprivation, high blood pressure, glaucoma, etc. Different medications are used for different reasons. 1. Lack of sleep: If the orbital pain is caused by lack of sleep, accompanied by migraines, the main thing is to regulate work and rest, go to bed early and get up early, avoid staying up late, and ensure that you get enough sleep every day, which is conducive to relief. If the pain symptoms are serious, you can use ibuprofen, acetaminophen and other analgesic drugs to relieve. 2. Hypertension: If the orbital swelling and pain, accompanied by migraine, is caused by increased pressure inside the cerebrovascular system due to fluctuation of blood pressure, which constantly stimulates the meninges, after a clear diagnosis, antihypertensive medications can be applied to alleviate the pain, and the commonly used medications are Irbesartan, Nifedipine, and so on. 3. Glaucoma: If it is due to acute attack of glaucoma, resulting in increased intraocular pressure, caused by orbital distension, accompanied by migraine, can be applied to hairy fruit rue base, mannitol and other drugs, rapid control of intraocular pressure. Application of drugs such as carteolol, levobunolol hydrochloride, etc., to reduce the amount of intraocular aqueous production and improve the above symptoms. Orbital distension accompanied by migraine headache, should avoid blindly self-abuse of drugs, it is recommended to seek medical treatment as soon as possible, through the improvement of relevant examinations, diagnosis, by the doctor’s guidance of reasonable use of drugs.