Uterine artery embolization (UAE) has been used in clinical practice for more than 20 years, mainly for the treatment of acute bleeding in gynecology and obstetrics, gynecologic tumors and vascular malformations, etc. In 1994, French scholars first reported the use of UAE to reduce intraoperative bleeding from uterine fibroids, and found that patients’ bleeding symptoms stopped and fibroids shrank after UAE treatment, and some patients were clinically cured after UAE treatment. With the improvement of radiological imaging technology and embolization materials, UAE treatment for uterine fibroids is rapidly developing with the advantages of less invasive, simple and easy to accept by patients. So which fibroids are suitable for interventional embolization? Generally speaking, interventional embolization is feasible for middle-aged women with large menstrual flow, even causing anemia, or clinical symptoms such as dysmenorrhea, except for subplasmic fibroids with tissues, submucosal fibroids less than 5 cm, and cervical fibroids after MRI. Methods: Under local anesthesia, a ballpoint pencil-thick catheter was punctured through the femoral artery under the right inguinal ligament and placed in the corresponding artery supplying the uterus, and the angiography showed the vascularity of the myoma; according to the DSA imaging performance, the uterine artery was super-selected for cannulation to the uterine artery, and uterine arteriography was performed to observe the course of the uterine artery and the staining of the uterine body angiography and the distribution of the lesion. According to the thickness of the uterine artery and the size and distribution of the lesion, special embolic pellets were injected to complete embolization of the uterine artery, and then the catheter and catheter sheath were removed, the puncture site was compressed for 10 min and then bandaged with pressure, and the right lower limb was braked for 12 h. The side effects of UAE were mainly: (1) post-embolization syndrome: including lower abdominal pain (more than 90%), fever (about 25%), irregular vaginal bleeding or vaginal discharge. (1) post-embolization syndrome: including lower abdominal pain (more than 90%), fever (about 25%), irregular vaginal bleeding or increased vaginal discharge (about 25%) and nausea and vomiting; all can be improved with symptomatic treatment; (2) lower limb soreness and weakness (50%-60%); no special treatment is needed; (3) necrotic tissue retention and drainage]. The main complications of UAE include hematoma and infection at the puncture site, thrombosis of the appendage, severe abdominal pain, local ischemia and necrosis of the pelvis and other organs, endometritis and irreversible necrosis of the uterus, retroperitoneal hematoma, ovarian hypofunction and transient amenorrhea, as well as postoperative urinary retention, uterine fistula formation, and sepsis.