In the dead of night, the calf often suddenly and involuntarily twitches one by one, although it does not hurt, but feels like insects, ants, soreness and swelling, a kind of discomfort that is difficult to name with words, leading to a long time unable to sleep. This is called restless leg syndrome. The main manifestation of restless legs syndrome belongs to the field of nervous system, and its main manifestation is the indescribable discomfort, ants walking, writhing, burning, sinking, swelling, soreness or tightness in the calf muscles bilaterally, accompanied by periodic involuntary calf twitching during sleep at night. The quieter the environment, the more obvious the symptoms are. At night, the symptoms are most prominent when the patient is about to change from light sleep to deep sleep. Because of this discomfort, which is difficult to express in words, patients often suffer from insomnia and can only walk back and forth restlessly. This leads to poor mental health, anxiety and depression, and worsening leg symptoms, creating a vicious cycle. A higher percentage of elderly people suffer from restless legs syndrome. Chinese medicine believes that this is caused by the deterioration of the body’s functions as the elderly age and the poor circulation of blood in the lower limbs. To date there is no clear cause for this disease, and some patients may have a family history. Most patients with restless legs syndrome have no abnormalities on neurological examination, but occasionally diabetic or uremic peripheral neuropathy may be found. The disease has a chronic course, which can last for decades, with significant fluctuations during the course of the disease, and is mostly benign in nature. Patients with uremia, diabetes mellitus, anemia, and vitamin B12 deficiency also present with symptoms of restless legs syndrome. In particular, 40% of patients with uremia suffer from restless legs syndrome. Therefore, if middle-aged or elderly people have symptoms of restless legs syndrome, it is important to go to the hospital to investigate whether there is an organic disease, so as not to delay the disease. Although restless leg syndrome only causes discomfort in the lower legs and insomnia, the concurrent organic disease of the patient can lead to a series of dangers. Elderly people with restless legs syndrome should avoid cold, strain, and emotional changes. You can also soak your feet in warm water every night or do some massage to make your calves feel comfortable and make it easier to sleep at night. At the same time, pay attention to sleep hygiene, should not drink a lot of coffee and alcohol, quit smoking is good for patients. However, these are only auxiliary measures, for the serious symptoms of this disease mainly need to use drugs for symptomatic treatment. At present, the application of more dopamine drugs, such as Medoxaba, 62.5mg ~ 125mg, taken every night; or anti-epileptic drugs, such as carbamazepine 0. 1 ~ 0.2g, taken every night; benzodiazepines also have a certain effect, such as clonazepam 1 ~ 2mg or diazepam 2.5mg ~ 5mg taken before bed. All of the above drugs are prescription drugs, choose to pay attention to adverse reactions, must be selected by the doctor according to the patient’s situation, the patient can not just use their own medication.