The precautions for the booster shot of Xin Guan vaccine mainly include before and after vaccination, of which before vaccination is to exclude some contraindications, and after vaccination is to pay attention to close observation of the adverse reactions of the vaccine, prohibit drinking alcohol and so on. Contraindications for booster shots include: fever, pregnant women, allergy to vaccine components, acute seizures, and people with acute infectious diseases. 1. Precautions: (1) The precautions before receiving booster shots of XKPV are mainly to screen the vaccinated population and suspend the vaccination for those who do not meet the vaccination conditions. Three days before the vaccination, you should maintain a good routine, keep a light diet, avoid drinking alcohol. (2) After receiving the booster shot of the new Crown pneumonia vaccine, you must observe closely for about 30 minutes before you can leave on your own, and you need to report any discomfort symptoms such as dizziness, chest tightness, palpitations, etc. to the vaccinating doctor in a timely manner. 2. Contraindications: patients with fever, pregnant women, people with a history of severe allergies, patients with malignant tumors undergoing chemotherapy within three months, acute seizures of epilepsy, acute infectious disease seizures, patients with severe cardiac abnormalities, people less than six months from the second injection of the new crown pneumonia vaccine, and so on. When receiving the booster shot of the new crown pneumonia vaccine, be sure to strictly follow the requirements of the local medical institutions or the CDC for vaccination. Tip: In this article, the terms “new coronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.