The symptoms of low back pain and leg weakness can be caused by a variety of reasons, and it is best to take the appropriate medication according to the different reasons. If the back pain and leg weakness is caused by lumbar disc herniation, you can take oral non-steroidal anti-inflammatory and analgesic drugs, such as diclofenac and celecoxib. You can also take oral nerve-nourishing drugs such as B vitamins and methylcobalamin tablets, and drugs to reduce edema of nerve roots such as Mai Zhi Ling and horse chestnut seed extract. If the weakness of the back and legs is caused by a lack of calcium, it is important to supplement the diet with protein and calcium, vitamins, trace elements, etc. It is also necessary to maintain daily outdoor sunshine time, rest and go to bed early and wake up early, do not stay up late, and quit bad habits. If it is caused by poor blood circulation throughout the body, it should be treated for the primary disease, such as hypertension, etc.