Calf muscle pain, walking pain is unbearable. First of all, the specific cause should be clarified, this situation may be caused by calf muscle strain, may also be caused by deep vein thrombosis, in addition may also be caused by lumbar intervertebral disc herniation compression of the nerves and so on. Different treatment programs need to be chosen according to the specific cause. For calf muscle injuries, cold compresses should be applied in the early stage, and after 48 hours, hot compresses, physical therapy and treatment to activate blood circulation and remove blood stasis can be considered. When the pain is obvious, local spraying of Yunnan Baiyao aerosol, external application of Foetalin ointment and oral non-steroidal anti-inflammatory drugs, such as Celecoxib, Loxoprofen sodium and so on, can have a better effect on relieving pain. In addition, massage, acupressure and acupuncture are also effective in relieving pain. Patients with lumbar disc herniation should first be given a hard bed, apply a waist cuff when moving, and avoid stooping and weight bearing and strenuous lumbar activities. Lumbar traction can be considered, the pain is obvious when it may be caused by compression of the nerve trunk caused by edema. In this case, mannitol and hormone can be used to relieve the symptoms, and surgery can also be considered for patients with spinal stenosis who have failed conservative treatment. For this situation caused by deep vein thrombosis, attention should be paid to rest in the acute stage, compression stockings can be applied, early thrombolysis, blood circulation, anticoagulation and improvement of microcirculation can be given to the treatment, the main drugs used are urokinase, low molecular heparin calcium, low molecular dextran anhydride, injectable thrombopoietin and so on. If the deep veins have formed sequelae, this case can also be treated by balloon and other surgical procedures.